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In Off the Scales, journalist Aimee Donnellan tells the fascinating story behind one of the most significant medical breakthroughs of the twentyfirst century: the development of Ozempic and other GLP1 drugs that are transforming the treatment of obesity and diabetes. What began as research into hormones that regulate blood sugar eventually led scientists to a medication capable of dramatically reducing appetite and body weight, raising hopes that the longsought medical solution to obesity might finally be within reach.
Through indepth reporting and compelling storytelling, Donnellan traces the decadeslong scientific journey that made these drugs possible, from early laboratory discoveries to the fierce pharmaceutical race to bring them to market. She reveals the key scientists, corporate rivalries, and unexpected breakthroughs that shaped the development of medications like Ozempic, while also highlighting overlooked researchers whose work laid the foundations for the GLP1 revolution.
But the story extends far beyond the laboratory. As these powerful drugs rapidly reshape the way society thinks about weight loss, Donnellan explores their broader consequences for culture, business, and public health. From changing beauty standards to ethical debates about access and misuse, Off the Scales examines how a single pharmaceutical innovation is influencing industries ranging from healthcare to fashion and food.
Insightful, timely, and thoughtprovoking, this book offers a clear and engaging look at the science, ambition, and social change behind the global race to treat obesity—and what it could mean for the future of medicine and society.
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